There is a scientific basis for staying up late to become stupid!

Often staying up late, the brain will become dull, and adequate sleep will make people maintain a smart brain. Those remarks full of "Why sleep for a long time before death? Doomed to sleep after death!" can really stand aside this time! This time the scientists filmed a video of the automatic cleaning of the brain during sleep.

Recently, scientists at Boston University published the latest research in the top international journal "Science". The results show that only in sleep, the brain will turn on the "auto-cleaning" mode to remove the memory dysfunction protein accumulated in the brain during the day.

Science: There is a scientific basis for staying up late to become stupid!

The research team of Dr. Laura Lewis, assistant professor of bioengineering at Boston University, conducted a study on 13 subjects between the ages of 23 and 33. The subjects put on an EEG cap and lay in a BMI device to sleep. The EEG will clearly show which sleep state the subject is in, and the MRI will measure the blood oxygen level.

Studies have found that during sleep, neuronal activity in the brain becomes less intense, and blood will periodically flow out of the brain, and a water-like fluid called Cerebro-Spinal Fluid (CSF) flows into it to flush rhythmically. brain. Cerebrospinal fluid is a "cleansing agent" for the brain. As early as 2013, studies have shown that cerebrospinal fluid contributes to the clearance of beta-amyloid. This means that the results of this study may provide new insights into Alzheimer's disease.

This cleaning work can only be done in the sleep phase, because in the waking state, blood fills the brain, and cerebrospinal fluid cannot enter the brain at all. The main focus of the study is the light sleep and deep sleep phases, which are the non-rapid eye movement (REM) phases. These two phases are very important for the brain to maintain a memory. At this time all neurons will become quiet, so the brain does not need too much oxygen at this time, which means that less blood flows into the brain. The cerebrospinal fluid will then flow into the brain for cleaning.

As people grow older, their brains usually produce fewer slow waves. This may affect the blood flow of the brain and reduce the fluctuation of cerebrospinal fluid during sleep, leading to the accumulation of toxic proteins and the decline of memory ability. Although researchers tend to evaluate these processes separately, it now appears that they are closely related. To further explore how aging affects sleep blood flow and cerebrospinal fluid activity in the brain, Lewis and her team plan to recruit older adults to participate in the next study.

This research reminds us that sleep is very important, staying up late reduces IQ. As you grow older, the cost of staying up late is too great. If the harmful substances metabolized by the brain during the day cannot be eliminated in time, autism and Alzheimer's disease may come to your door when you are old.